Detecting Counterfeit Pharmaceuticals through UV Spectrophotometry

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Determination of Sulfamethoxazole and Trimethoprim in Pharmaceuticals by Visible and UV Spectrophotometry

A method for the simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP), based on a direct determination of SMX after diazotization and coupling with 2-naphthol by visible spectrophotometry and an indirect determination of TMP in the UV region by difference was developed. By the suggested procedure, it was possible to analyze SMX and TMP in pharmaceutical preparations witho...

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Determination of Sulfamethoxazole and Trimethoprim in Pharmaceuticals by Visible and UV Spectrophotometry

A method for the simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP), based on a direct determination of SMX after diazotization and coupling with 2-naphthol by visible spectrophotometry and an indirect determination of TMP in the UV region by difference was developed. By the suggested procedure, it was possible to analyze SMX and TMP in pharmaceutical preparations witho...

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determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and uv spectrophotometry

a method for the simultaneous determination of sulfamethoxazole (smx) and trimethoprim (tmp), based on a direct determination of smx after diazotization and coupling with 2-naphthol by visible spectrophotometry and an indirect determination of tmp in the uv region by difference was developed. by the suggested procedure, it was possible to analyze smx and tmp in pharmaceutical preparations witho...

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Trojan drugs: counterfeit and mislabeled pharmaceuticals in the legitimate market.

Over the past five years, there have been over 140 reported incidents of counterfeit and mislabeled drugs being sold by legitimate pharmacies in the United States. Thousands of patients have consumed these medications, sometimes with dire consequences. The extent of counterfeits in the legitimate market, however, is unknown. It is certain that the detected incidents of fakes are a fraction of t...

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ژورنال

عنوان ژورنال: Biophysical Journal

سال: 2016

ISSN: 0006-3495

DOI: 10.1016/j.bpj.2015.11.2620